Aims: Promoting healthy lifestyles among students is crucial, as they can facilitate health education within families and communities. This study aimed to assess health-promoting lifestyles among dormitory-residing students at North Khorasan University of Medical Sciences. Instrument & Methods: This cross-sectional study was conducted in 2024 among 348 dormitory-resident students at North Khorasan University of Medical Sciences, Iran, selected via multistage sampling. Data on demographics and health-promoting behaviors were collected using a validated 49-item Persian HPLP-II questionnaire. Data were analyzed using SPSS 22, which included descriptive statistics, t-tests, and ANOVA. Findings: Of the 348 dormitory-residing students (mean age 22.42±2.32 years; 34.8% male), the mean health-promoting lifestyle score was 135.82±19.35. Females exhibited significantly higher total and subscale scores than males (p<0.05). Employed students scored higher in total, health responsibility, physical activity, and nutrition (p<0.05). Significant differences were observed based on educational level, mother’s education, father’s occupation, and family income (p<0.05), with lower scores generally associated with lower socioeconomic factors. No differences were found by marital status (except for health responsibility), semester, field of study, or mother’s occupation. Conclusion: Sociodemographic factors, including gender, employment, educational level, mother’s education, father’s occupation, and family income play a significant role in health-promoting lifestyles.