Health Education and Health Promotion

en Analysis of Maternal Risk Factors Associated with Non-Syndromic Orofacial Cleft Among Newborns at Celebes Cleft Center in Makassar <div style=text-align: center;></div> <div style=text-align: justify;>Aims: Non-syndromic orofacial cleft (NSOFC) is a congenital facial anomaly of cleft lip, cleft palate, or both, most commonly affecting the craniofacial region and oral cavity. The etiology is multifactorial, combining endogenous (genetic) with environmentally influenced exogenous factors. This study aimed to determine and analyze the risk factors for the incidence of NSOFC. Materials & Methods: This case-control study was conducted at Celebes Cleft Center in Makassar. The case group consisted of 80 newborns with cleft lip and palate, and the control group consisted of 106 newborns without cleft lip and palate. Data collected included sex, type of NSOFC, age of respondents, educational level, risk factors for NSOFC incidence from patient medical records and interview results. Data were collected in an Excel table and analyzed using the Stata program using the Chi-square test and multiple logistic regression. Findings: The results showed that NSOFC mostly occurred in newborns of male gender (58.75%). The most common type of NSOFC was cleft lip accompanied by cleft palate then cleft lip, and the least was cleft palate. Maternal risk factors that were significant for the incidence of cleft lip and palate/NSOFC were maternal occupation (OR=25.037; 95%CI=5.812-222.113; p<0.001), family history of orofacial cleft (OR=11.666; 95%CI=1.493-522.396; p=0.005), history of tobacco smoke exposure during pregnancy (OR=2.64; 95%CI=1.355-5.187; p=0.002). The most dominant risk factor was maternal occupation. Conclusion: The type of maternal occupation, family history of orofacial cleft, and maternal history of tobacco smoking are risk factors for the incidence of lip and palate cleft or NSOFC.</div> <div></div> Cleft Lip,Palate,Cleft Palate,Risk Factors, 47 52 http://hehp.modares.ac.ir/browse.php?a_code=A-10-79815-1&slc_lang=en&sid=4 B. Rusdi 1003194753284600317546 1003194753284600317546 Yes Department of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia A.Z. Abdullah 1003194753284600317547 1003194753284600317547 No Department of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia W. Wahiduddin 1003194753284600317548 1003194753284600317548 No Department of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia I.L. Maria 1003194753284600317549 1003194753284600317549 No Department of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia U. Salmah 1003194753284600317550 1003194753284600317550 No Department of Biostatistics, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia B. Nazaruddin 1003194753284600317551 1003194753284600317551 No Department of Health Administration and Policy, Faculty of Public Health, Hasanuddin University, Makassar, Indonesia