en <span style=font-size:12pt><span style=font-family:Times New Roman,serif><b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4f81bd>Aims:</span></span></span></b><b> </b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif>Substance abuse in adolescents is caused by many factors, including family conflicts, negative parenting models, and family estrangement. The aim of this study was to determine the relationship between resilience and family functioning with drug use risk behavior among adolescents in Limo District, Depok city, Indonesia. </span></span></span></span><br> <span style=font-size:12pt><span style=font-family:Times New Roman,serif><b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4f81bd>Instruments & Methods:</span></span></span></b><b> </b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif>This descriptive correlational study with a cross-sectional approach was conducted on adolescents aged 10-15 years who lived in Limo District, Depok, Indonesia. 315 adolescents were selected by simple random sampling method. Walsh Family Resilience Questionnaire was used to measure family resilience, and Family Assessment Device was used to measure family functioning. Data analysis was performed using chi-square test and logistic regression analysis. </span></span></span></span><br> <span style=font-size:12pt><span style=font-family:Times New Roman,serif><b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4f81bd>Findings:</span></span></span></b><b> </b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif>Family resilience (p=0.011) and family functioning (p=0.001) were significantly related to drug use risk behavior. Adolescents whose families have poor resilience are 1.694 times more likely to engage in risky drug behaviors than adolescents whose families have good resilience. Also, adolescents who have poor-functioning families are 2.054 times more at risk of risky drug behaviors than adolescents whose families function well.</span></span><b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif></span></span></b></span></span><br> <span style=font-size:12pt><span style=font-family:Times New Roman,serif><b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4f81bd>Conclusion:</span></span></span></b><span lang=EN-SG style=font-size:10.0pt><span style=font-family:Cambria,serif> Adolescents whose families have low resilience and whose families have poor functioning are 60.7% more likely to exhibit drug use risk behavior.</span></span></span></span><br> <br> <span style=font-size:medium><span new= roman= style=font-family: times=><span style=color:#000000><span style=font-style:normal><span style=font-weight:400><span style=white-space:normal><span style=text-decoration:none><span style=font-family:Cambria, serif></span></span></span></span></span></span></span></span> Adolescent,Drug Abuse,Family,Psychological Resilience, 239 243 http://hehp.modares.ac.ir/browse.php?a_code=A-10-72713-1&slc_lang=en&sid=4 R. Ritanti 1003194753284600296348 1003194753284600296348 No Nursing Department, Faculty of Health Sciences, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta, Indonesia I. Permatasari 1003194753284600296349 1003194753284600296349 No Nursing Department, Faculty of Health Sciences, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta, Indonesia Y. Nurdiantami 1003194753284600296350 1003194753284600296350 Yes Public Health Department, Faculty of Health Sciences, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta, Indonesia