en <span style=font-size:10pt><span style=unicode-bidi:embed><span new= roman= style=font-family: times=><b><span cambria= style=font-family:><span style=color:black>Aims:</span></span></b><span cambria= style=font-family:><span style=color:black> Self-care behaviors and standard precautions are important for maintaining nurses' health. This research aimed to evaluate the relationship between nurses’ self-care and standard precaution observance in intensive care unit during COVID-19.</span></span></span></span></span><br> <span style=font-size:10pt><span style=unicode-bidi:embed><span new= roman= style=font-family: times=><b><span cambria= style=font-family:><span style=color:black>Instruments & Methods:</span></span></b><span cambria= style=font-family:><span style=color:black> This descriptive-analytical research was conducted on the ICU nurses at Mashhad University of Medical Sciences. A total of 140 nurses were included in the research through convenience sampling. The data were collected using demographic survey questions, Self-Care Inventory-Revised (SCI-R), and Compliance with Standard Precautions Scale (CSPS).</span></span></span></span></span><br> <span style=font-size:10pt><span style=unicode-bidi:embed><span new= roman= style=font-family: times=><b><span cambria= style=font-family:><span style=color:black>Findings:</span></span></b><span cambria= style=font-family:><span style=color:black> The greatest self-care means among the participants was in the professional dimension (40.1±4.41), and the lowest means of self-care was in the psychological dimension (26.97±3.55). The highest and lowest score of standard precautions was 20 and 3, respectively. The average precaution observance was 13.99±2.931. There was a positive and significant correlation between self-care and observance of standard precautions of nurses (r=0.224; p=0.008).</span></span></span></span></span><br> <span style=font-size:10pt><span style=unicode-bidi:embed><span new= roman= style=font-family: times=><b><span cambria= style=font-family:><span style=color:black>Conclusion:</span></span></b><span cambria= style=font-family:><span style=color:black> Nurses in intensive care units in COVID-19 pandemic pay little attention to their self-care. Self-care in the professional dimension receives relative attention, and in the psychological dimension, receives the least attention. The standard precautions in COVID-19 pandemic is not at an acceptable level, and there is a direct and positive correlation between self-care and observing standard precautions.</span></span></span></span></span> Covid-19,Epidemic,Intensive care,Infectious diseases,Nurse Self-care,Standard precautions. 3 10 http://hehp.modares.ac.ir/browse.php?a_code=A-10-71482-2&slc_lang=en&sid=4