en <div style=text-align: justify;><strong>Aims:</strong> Epidemiological transition of acute and infectious diseases to non-communicable ones, aging population, together with rapid lifestyle changes all have given rise to prevalence rate of cardiovascular diseases (CVDs). Thus, it is of utmost importance to reflect on lifestyles, especially in this period. The main purpose of the present study was to assess lifestyle in patients affected with myocardial infarction (MI).<br> <strong>Instruments & Methods:</strong> This study was a cross-sectional study examining health-related lifestyle behaviors in patients with MI in 2019. To this end, a total number of 176 patients were selected using purposive and convenience sampling methods. The research instrument was also the Health-Promoting Lifestyle Profile II (HPLP-II) as a standardized self-report questionnaire. The data analyzed using IBM SPSS 22 and the generalized linear models were used. Moreover, coefficient at a significance level less than 0.05.<br> <strong>Findings:</strong> The results of Wilks’ lambda distribution revealed that the effect of gender on the linear combination of the dependent variable (i.e. lifestyle) was significant and 11.4% of changes in this variable had resulted from variation in gender. Besides, the results demonstrated that health responsibility scores in men were on average 2.703 lower than those obtained by women. This relationship was also significant and its effect size was by 3.3% (p= 0.016).<br> <strong>Conclusions:</strong> It was concluded that the concept of lifestyle can be an analysis tool to better understand differences between genders, as an effective variable in adopting a healthy lifestyle, especially in patients suffering from MI.</div> Lifestyle, Myocardial Infarction, Gender Identity, Patients 149 153 http://hehp.modares.ac.ir/browse.php?a_code=A-10-39988-3&slc_lang=en&sid=4 H. MohseniPouya hosseinmohsenipouya@gmail.com 1003194753284600178738 1003194753284600178738 Yes Department of Nursing, School of Nursing, Mazandaran University of Medical Sciences, Sari, Iran Y. Jannati 1003194753284600178739 1003194753284600178739 No Department of Nursing, School of Nursing, Mazandaran University of Medical Sciences, Sari, Iran S.A. Naghibi 1003194753284600178740 1003194753284600178740 No “Department of Public Health, Faculty of Health” and “Health Sciences Research Center”, Mazandaran University of Medical Sciences, Sari, Iran J. Yazdani-Charati 1003194753284600178741 1003194753284600178741 No Department of Biostatistics, School of Health, Mazandaran University of Medical Sciences, Sari, Iran