en <div style=text-align: justify;><strong>Aims: </strong>To find <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928259305912121879>prevalence</gwmw> and related factors of diabetes mellitus in rural regions of <gwmw class=ginger-module-highlighter-mistake-type-1 id=gwmw-15548928259303699953893>Grash</gwmw> Town located in central Iran (Fars province) composed of 25 rural regions.<br> <strong>Instruments & Methods:</strong> This cross sectional study was conducted on a sample of 1523 adults aged ≥30 years, living in rural regions of <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928274717594715978>Grash Town</gwmw> during 2015-2016. We used stratified random sampling. Participants were invited by calls and informed consent was obtained from all. We checked HbA1c of participants and demographic information, past medical history, and some risk factors (BMI, <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928313185948539474>familial</gwmw> and personal history of diabetes and level of physical activity) among them were investigated. Cases with HbA1C≥6<gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928319690021909531>.</gwmw>5% were considered diabetics. Pregnant women and people with <gwmw class=ginger-module-highlighter-mistake-type-1 id=gwmw-15548928340224784684242>haemoglobinopathies</gwmw>, anemias, and chronic liver/renal diseases were excluded. Data were analyzed, using SPSS19 software. <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928351727818016048>Statistical significant level</gwmw> was <0.05 in this study.<br> <strong>Findings:</strong> In this study, 507<gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928362828992929093>(</gwmw>33.3%) cases were with HbA1c≥6<gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928362829044202734>.</gwmw>5%, of whom 241 (15.8%) were previously diagnosed as diabetic. Diabetes was associated with age (p<0.001), occupation (p=0.04), education (p<0.001), marital status (p<0.001), BMI (p<0.001), and familial history (p<0.001). Age ≥ 50 years, <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928388332762796866>familial</gwmw> history of diabetes, obesity/overweight, unemployment, low educational attainment, and loss of <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15548928388337535008496>partner</gwmw> were all more frequent in diabetics.<br> <strong>Conclusion:</strong> Prevalence of diabetes measured by HbA1c in this study was greater than most previous studies in Iran. However, most studies have used FBS and we need further studies to determine optimal threshold of HbA1c for diagnosis of diabetes in Iranian population. High risk people should be focused in preventive and control programs.</div> Diabetes Mellitus, Glycated Hemoglobin A, Prevalence, Screening, Risk factor 89 93 http://hehp.modares.ac.ir/browse.php?a_code=A-10-42747-1&slc_lang=en&sid=4 H. Soori 1003194753284600119489 1003194753284600119489 No Safety Promotion and Injury Prevention Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran M.N. Mohammadi dr.mn_mohammadi@yahoo.com 1003194753284600119490 1003194753284600119490 Yes Public Health Faculty, Shahid Beheshti University of Medical Sciences, Tehran, Iran J. Yoosefi Lebni 1003194753284600119491 1003194753284600119491 No Public Health Faculty, Iran University of Medical Sciences, Tehran, Iran