en <strong>Aim:</strong> Breast cancer is the most common cancer in women<gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15527224745316247159441>.</gwmw>The Health Education Campaign (HEC) is an important educational strategy for breast cancer screening. The aim of this study was to investigate the effect of the (HEC) based training on the knowledge, attitudes, and practices of women, regarding breast cancer screening methods.<br> <strong>Materials & Methods:</strong> This was a pre- and post-quasi-experimental study conducted among 200 women over 20 years in Mazandaran Province. A self-made 34-item questionnaire was used to collect the data. A pretest was performed before the educational intervention and a <gwmw class=ginger-module-highlighter-mistake-type-1 id=gwmw-15527224775638749151853>posttest</gwmw> was conducted 12 weeks after the intervention. The data were analyzed by logistic regression, Pearson correlation coefficient, and one way ANOVA, using SPSS 22.<br> <strong>Findings: </strong>The mean age of the women was 35.16 years. Based on paired t-test, the difference in the mean scores of knowledge and attitudes regarding screening methods in the women was significant (p≤0<gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15527224801913913681213>.</gwmw>0001) before and after the intervention. Also, based on the <gwmw class=ginger-module-highlighter-mistake-type-1 id=gwmw-15527224815121993409741>macnemar</gwmw> test, the difference between the early detection of breast self-examination (BSE) and clinical breast examination (CBE) was <gwmw class=ginger-module-highlighter-mistake-type-3 id=gwmw-15527224815126575596114>significant</gwmw> in the women studied before and after the educational intervention.<br> <strong>Conclusion: </strong>According to the results of the study, the intervention had been able to change the knowledge, attitudes, and behaviors of women regarding breast cancer and early detection methods.<br> Health Education Campaign, Breast Cancer, Screening 21 25 http://hehp.modares.ac.ir/browse.php?a_code=A-10-39988-2&slc_lang=en&sid=4 H. Mohsenipouya 1003194753284600114492 1003194753284600114492 No Health Education & Promotion Department, Nursing Faculty, Mazandaran University of Medical Sciences, Sari, Iran S. Naghibi anaghibi1345@yahoo.com 1003194753284600114493 1003194753284600114493 Yes “Health Sciences Research Center” and “Public Health Department, Health Faculty”, Mazandaran University of Medical Sciences, Sari, Iran D. Shojaizadeh 1003194753284600114494 1003194753284600114494 No “Institute of Public Health Research” and “Health Education & Promotion Department, Public Health Faculty”, Tehran University of Medical Sciences, Tehran, Iran A. Montazeri 1003194753284600114495 1003194753284600114495 No Health Metrics Research Centre, Iranian Institute for Health Science Research, Tehran University of Medical Sciences, Tehran, Iran