en <span style=font-size:12pt><span style=text-justify:inter-ideograph><span style=font-family:Times New Roman,serif><b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4472c4>Aims:</span></span></span></b><b> </b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>The aim of this study was to analyze the effect of a combination of music therapy and breathing exercises on anxiety and physiological parameters in patients using mechanical ventilation. </span></span></span></span></span></span><br> <span style=font-size:12pt><span style=text-justify:inter-ideograph><span style=font-family:Times New Roman,serif><b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4472c4>Materials & </span></span></span></b><b><span lang=EN style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4472c4>Methods:</span></span></span></b><b> </b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>The sample of this randomized controlled trial included 70 patients assigned to a treatment group of 35 patients and a control group of 35 patients. The proposed intervention was a combination of music therapy and deep breathing exercises carried out for 30 minutes twice a day for five days at 09:00 AM and 4:00 </span></span></span><span style=font-size:10.0pt><span style=font-family:Cambria,serif>PM<span style=color:black>. In patients receiving mechanical ventilation, the following settings were used: synchronized intermittent mechanical ventilation, adaptive support ventilation, pressure support ventilation, continuous positive airway pressure, and </span></span></span><span lang=EN style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>duo positive airway pressure</span></span></span><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>. Measurement of anxiety levels was done by the State-Trait Concern Inventory (Form Y) and assessing physiological parameters, such as blood pressure, mean arterial pressure, heart rate, respiration</span></span></span> <span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>rate, and oxygen saturation. Data analysis was done using the paired t-test, Wilcoxon test, Mann-Whitney U test, and MANOVA at p<0.05.</span></span></span></span></span></span><br> <span style=font-size:12pt><span style=text-justify:inter-ideograph><span style=font-family:Times New Roman,serif><b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4472c4>Findings:</span></span></span></b><b> </b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>Differences were observed between the two groups in anxiety levels (p=0.001), heart rate (p=0.001), and respiration</span></span></span> <span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>rate (p=0.001). There were no differences between the two groups in systolic blood pressure (p=0.549), diastolic blood pressure (p=0.891), mean arterial pressure (p=0.571), and oxygen saturation (p=0.827). </span></span></span></span></span></span><br> <span style=font-size:12pt><span style=text-justify:inter-ideograph><span style=font-family:Times New Roman,serif><b><span style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:#4472c4>Conclusion:</span></span></span></b><b> </b><span lang=EN style=font-size:10.0pt><span style=font-family:Cambria,serif><span style=color:black>The combination of music therapy with deep breathing exercises affects patient anxiety and physiological parameters with minimal risks.</span></span></span></span></span></span> Music Therapy,Breathing Exercise,Anxiety,Vital Signs,Noninvasive Ventilation, 591 597 http://hehp.modares.ac.ir/browse.php?a_code=A-10-70384-8&slc_lang=en&sid=4