en <div style=text-align: justify;><strong>Aims: </strong>The present study is aimed to determine the role of acceptance and mindfulness therapy on physical activity increment and obesity decrement in the patients suffering from heart disease in Bandar Abbas.<br> <strong>Participants & Methods:</strong> In terms of type, the study is applied one and in terms of research method, it is a quasi-experimental study along with a pre-test-post-test with a control group. The statistical population of the study involves all the patients suffering from heart disease being overweight who had visited Bandar Abbas’ hospitals during 2018-2019 and according to angiographic reports, eclipse was more than 50% and BMI≥30. In the present study, an available sampling method was used. The population size was 20 that 10 were assigned to experimental group and 10 to control group. The data were collected through making use of physical activity level, body mass index (BMI) questionnaire. Data were analyzed using covariance analysis and SPSS software.<br> <strong>Findings:</strong> Acceptance therapy had been effective on physical activity increment and body mass decrement of the patients suffering from heart disease.<br> <strong>Conclusion:</strong> Mindfulness-based therapy can be considered as a non-invasive treatment. This clinical trial will result in more effective mindfulness-based interventions as a complementary treatment in primary care for people with overweight and obesity.</div> Mindfulness-Based Therapy, Activity Increment, Body Mass Decrement, Obesity, Heart Diseases 73 77 http://hehp.modares.ac.ir/browse.php?a_code=A-10-54137-1&slc_lang=en&sid=4 A. Mohammadzadeh masoudnader@gmail.com 1003194753284600171268 1003194753284600171268 Yes Cardiovascular Surgery Department, School of Medicine & Allied Medical Sciences, Ardabil University of Medical Sciences, Ardabil, Iran N. Ghanbari 1003194753284600171269 1003194753284600171269 No Psychology Department, Ardabil Branch, Islamic Azad University, Ardabil, Iran S. Taj Abadipour 1003194753284600171270 1003194753284600171270 No Psychology Department, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran S. Arabnejad 1003194753284600171271 1003194753284600171271 No Psychology Department, Rudehen Branch, Islamic Azad University, Rudehen, Iran