en Original Research <strong>Aims:&nbsp;</strong>Pulmonary tuberculosis disproportionately affects the productive age group and has&nbsp;a tendency to spread to household contacts, especially vulnerable populations like children&nbsp;from low socioeconomic backgrounds. This study aimed to develop a life skills education&nbsp;model for tuberculosis patients, employing an effective life skills education strategy to prevent&nbsp;tuberculosis transmission, particularly among household contacts.<br> <strong>Materials & Methods:</strong> This quantitative quasi-experimental study used a two-group pre-test&nbsp;and post-test design. The study population comprised all tuberculosis patients in the North&nbsp;Sumatra region. The sample included 127 patients from urban areas and 126 patients from&nbsp;rural areas assigned to the intervention and control groups. The non-parametric Friedman test&nbsp;was used to examine changes in knowledge, attitudes, and practices regarding the prevention&nbsp;of tuberculosis transmission among household contacts. Concurrently, the Mann-Whitney test&nbsp;was applied to compare scores between the groups.<br> <strong>Findings:&nbsp;</strong>Post-intervention analysis revealed significant changes in attitudes for both urban&nbsp;and rural groups (p=0.0001), with no significant difference in the magnitude of these changes&nbsp;between the two areas (p>0.05). While practice scores improved significantly following&nbsp;the intervention (p<0.05), no significant difference in changes in practice scores was found&nbsp;between rural and urban areas when comparing the first and third tests (p>0.05).<br> <strong>Conclusion:&nbsp;</strong>Health education delivered via the lecture method, incorporating the life skills&nbsp;education module, effectively improves knowledge, attitudes, and actions in both urban and&nbsp;rural settings. Interpersonal Skills, Pulmonary Tuberculosis, Household Contacts 107 113 http://hehp.modares.ac.ir/browse.php?a_code=A-10-2-9375&slc_lang=en&sid=4 Asriwati Amirah asriwatiamirah@gmail.com 1003194753284600380348 1003194753284600380348 Yes Teguh Suharto teguhsuharto@gmail.com 1003194753284600380349 1003194753284600380349 No Nur Aini aini6828@yahoo.com 1003194753284600380350 1003194753284600380350 No Rara Jaka Desy rarajakadesy@gmail.com 1003194753284600380351 1003194753284600380351 No Neni Ekowati neniekowati@gmail.com 1003194753284600380352 1003194753284600380352 No Krisna Dona BR Sembiring krisnadonabrsembiring@gmail.com 1003194753284600380353 1003194753284600380353 No Azniah Syam azniahsyam@gmail.com 1003194753284600380354 1003194753284600380354 No Melyana Malik melyana130999@gmail.com 1003194753284600380355 1003194753284600380355 No